PRODUCT DETAILS

About Apletro 5mg Tablet

LETROZOLE belongs to the group of anti-cancer medicines called aromatase inhibitors used to treat breast cancer in women who have gone through menopause (cessation of menses periods). Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen.
 

Uses of Apletro 5mg Tablet

Breast cancer

Medicinal Benefits of Apletro 5mg Tablet

LETROZOLE belongs to the group of anti-cancer medicines called aromatase inhibitors. LETROZOLE is used to treat breast cancer in women who have gone through menopause (cessation of periods). Breast cancer is a type of cancer that develops in breast cells which are stimulated by female sex hormone called estrogen. LETROZOLE works by blocking the aromatase enzyme, which is involved in the production of estrogens. The cancer cells require estrogen for their growth, so by blocking the enzyme LETROZOLE prevents the growth of cancer cells. Thereby, LETROZOLE helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.

Directions for Use

Take LETROZOLE with or without food. Do not chew or break the tablet; swallow it as a whole with a glass of water. Take LETROZOLE at the same time every day. LETROZOLE should not be taken unless prescribed by a doctor. Based on your medical condition, your doctor will advise for how long you need to take LETROZOLE.

Side Effects of Apletro 5mg Tablet

Like all medicines, LETROZOLE can also cause side-effects, although not everybody experiences them. Hypercholesterolemia (increased cholesterol levels), tiredness, weakness, increased sweating, feeling unwell, pain in joints, and hot flushes (feeling of warmth) are the common side-effects of LETROZOLE. Please consult your doctor if you experience any of these side-effects persistently.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Do not take LETROZOLE if you are allergic to any of its contents, not yet gone through menopause (still get your periods). To treat you condition effectually continue taking LETROZOLE for as long as your doctor has prescribed. Do not stop LETROZOLE midway. Talk to your doctor before taking LETROZOLE if you have osteoporosis (thinning of bones), bone fractures, severe liver or kidney disease. LETROZOLE may cause inflammation in tendons or tendon injury; contact your doctor if you observe any sign of tendon pain or swelling while taking LETROZOLE.  Avoid taking LETROZOLE if you are pregnant or breastfeeding. LETROZOLE causes drowsiness and dizziness, so drive only if you are alert. LETROZOLE should not be given to children as the safety has not been established. Avoid consuming alcohol along with LETROZOLE as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications before taking LETROZOLE to rule out any side-effects. 

Drug Interactions

Drug-Drug Interaction:

LETROZOLE may interact with antidepressants (like citalopram, escitalopram) and anticancer used for breast cancer (tamoxifen). 

Drug-Disease Interaction:

 LETROZOLE should not be given tp the patients with high cholesterol, osteoporosis (thinning of bone), and liver disease.

Safety Advice

ALCOHOL

• You are recommended to avoid alcohol consumption while taking LETROZOLE to avoid unpleasant side-effects. Alcohol intake, along with LETROZOLE, may cause increased drowsiness.

PREGNANCY

• LETROZOLE is pregnancy category D medicine so, should not be taken during pregnancy.

BREAST FEEDING

• LETROZOLE should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby.

DRIVING

• LETROZOLE may cause dizziness and drowsiness, do not drive or operate heavy machinery if you feel dizzy.

LIVER

• It is safe to take LETROZOLE if prescribed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

KIDNEY

• It is safe to take LETROZOLE if prescribed. Please consult your doctor if you have kidney impairment or any concerns regarding this. No dosage adjustment is required for kidney patients with creatinine clearance greater than 10 mL/min.